plenity drug interactions

For a complete list of participating pharmacies, see pharmacies. Ask your pharmacist or doctor for advice if you are confused by the medical jargon. With Plenity, you may find it easier to eat less and feel satisfied within weeks of starting your new routine. It has been cleared by the FDA for adults. You can either ask your healthcare provider about Plenity, or visit MyPlenity.com to start a telehealth experience with a licensed physician. Accessibility Please choose the category that best describes you. I could still eat the foods my family was eating, and still make progress toward my weight. Major drug interactions that are life-threatening are not common, but are of serious concern. Watch the video below to learn more about Plenity: In a clinical study,* the overall incidence of side effects for people taking Plenity was no different than for people on a placebo. As an alternative option to current pharmacological AOTs, OSH may address an existing clinical gap in weight management. monograph. PMC Plenity has been shown to be effective, safe and well-tolerated in clinical studies. The concomitant use of SSRIs and SNRIs including PRISTIQ with MAOIs increases the risk of serotonin syndrome. The site is secure. All rights reserved. Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox. Body weight management in overweight and obese breast cancer survivors. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Plenity is not absorbed into the bloodstream. Developed, clinically tested, and manufactured by Gelesis. Rx Only. The overall incidence of side effects with Plenity was no different than placebo. No. WebBlood levels of an interacting drug may rise, leading to toxicity. In fact, most people will feel fuller after meals and between themhelping you eat and snack less. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). This tool explains what the interaction is, how it occurs, the level of significance (major, moderate, or minor) and usually a suggested course of action. This site needs JavaScript to work properly. Not all drug interactions are bad. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you miss a pre-meal dose, take Plenity with 16 oz. antihemophilic factor (factor VIII, human)/von Willebrand factor antihemophilic factor (factor VIII, recombinant). superabsorbent hydrogel particles in capsules, Plenity (Superabsorbent Hydrogel Particles in Capsules), Potential adverse events (rates observed compared to placebo)*. To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. Consult your doctor before breastfeeding. The water We comply with the HONcode standard for trustworthy health information. NCI CPTC Antibody Characterization Program. Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. Plenity passes through the digestive system, maintaining its three-dimensional structure in the stomach and small intestine before breaking down in the colon. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. Developed, clinically tested, and manufactured by Gelesis. However, as with all CNS-active drugs, patients should be advised to avoid alcohol consumption while taking PRISTIQ. Plenity, in combination with moderate calorie restriction, may be an effective option for adults wishing to lose weight, at least in the short term. Do not stop your medication without talking to your healthcare provider first. The structures and properties of our superabsorbent hydrogel, Plenity, are very different from fiber. OSH offers a nonsystemic approach to weight management for patients who are diagnosed with overweight or obesity. Contact a doctor right away if problems occur. Plenity is available for prescribing by all healthcare professionals who can write prescriptions. OSH is one of the only prescription antiobesity therapeutics (AOTs) that can be utilized in overweight patients with BMI equal to 25 to 30 kg/m2, regardless of comorbidity status. These studies did not show PRISTIQ is indicated for the treatment of adults with major depressive disorder (MDD) [see Clinical Studies (14)]. Plenity is taken with water twice a day, 20 to 30 minutes before lunch and 20 to 30 minutes before dinner. Keywords: Closely monitor for bleeding for patients receiving an antiplatelet or anticoagulant drug when PRISTIQ is initiated or discontinued, Drugs that are Primarily Metabolized by CYP2D6. Create a FREE Epocrates Online account to access full-color images of medications within the drug FDA Approved: Yes (First approved April 12, 2019) metformin efficacy (absorption possibly decreased), Monitoring Parameters Plenity has not been studied in people under the age of 22. Please check with your plan provider for reimbursement details. Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. Careers. Drug interactions can also contribute to the cost of healthcare, as a serious drug interaction could result in injury, hospitalization, or rarely, death. Do I need to see a doctor in person to get Plenity? squared, and then multiply by a factor of 703. Brand name: Plenity Your patients and Contact a doctor right away if problems occur. Metabolic enzymes in your body and your genetics. Original dose should be taken when co-administered with PRISTIQ 100 mg or lower. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. In both treatment groups, most (>95%) adverse events were assessed by the investigator as mild or moderate in intensity. Usually, your doctor and pharmacist will have already done this with your prescription medications, but it's a good idea to double check and learn about these medications yourself. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. $98/4-week supply. Plenity is a prescription-only weight loss aid. Disclaimer. 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In a premarketing study of 436 people, dropout rates from adverse effects (4%) were similar in the treatment and placebo groups.1, Data are limited about the effectiveness of Plenity. Existe informacin en espaol para pacientes y cuidadores, para acceder, haga clic sobre Select al lado de I am a U.S. As you continue to use it, you feel fuller throughout the day. Web7.3 Alcohol A clinical study has shown that PRISTIQ does not increase the impairment of mental and motor skills caused by ethanol. 50 mg Tablet: light pink, square pyramid tablet debossed with "W" over "50" on the flat side Hypersensitivity to desvenlafaxine succinate, venlafaxine hydrochloride or to any excipients in the PRISTIQ formulation. Characteristics and Weight Loss Practices From a Cohort of 20,000 Patients Using Direct-to-Consumer Telehealth: Observational Cross-sectional Study. Their average weight loss was 10% (about 22 pounds). Bookshelf An official website of the United States government. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Any person under the age of 22 should not take Plenity. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Plenity has been shown in a clinical study to have a proven safety profile and is as well tolerated as a placebo (a capsule with inactive ingredients).*. Aronne LJ, Anderson JE, Sannino A, Chiquette E. Obes Sci Pract. There were no serious adverse events (SAEs) in the Plenity treatment group, whereas there was one (1) SAE in the placebo treatment group. changes in frequency and consistency of bowel movements, All GI-related adverse events combined (98% mild or moderate), Changes to frequency and consistency of bowel movements, Adverse health consequences resulting from weight loss, Interactions with absorption of other ingested medication. desipramine, atomoxetine, dextromethorphan, metoprolol, nebivolol, perphenazine, tolterodine. Treatment for: Weight Loss (Obesity/Overweight). Plenity (cellulose and citric acid) Consumer information. Note that the telehealth option for Plenity is now available in all 50 U.S. states. You must drink 16 ounces of water for Plenity to work. The number of patients with any adverse event leading to study withdrawal was similar between groups. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Data sources: WebConstipation or not having bowel movements often (5 to 9%) Headache (7%) Stomach pain (5%) Nausea (5%) In clinical studies, there were no overall differences in the rate of side effects between those using Plenity and those using placebo. It is made from naturally derived building blockscellulose and citric acid. Once prescribed, Plenity will be shipped to your home via free 2-day delivery. This series is coordinated by Allen F. Shaughnessy, PharmD, assistant medical editor. Plenity Patient Information is supplied by Cerner Multum, Inc. and Plenity Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights. You can visit MyPlenity.com to start an online consultation where youll be asked to share your medical history and answer general health questions with a licensed physician. The member experience delivers practical and trusted advice from registered dietitians and medical experts to help make the changes that feel right for you. Age restrictions may apply to the purchase of certain drugs. Patients and physicians can contact RxPathways at (866) 706-2400 or visit the website for more information on these programs www.pfizerrxpathways.com. Select one or more newsletters to continue. Plenity is NOT available at retail pharmacies. The particles break down in the colon and are excreted in the stool without being absorbed. This page cannot be displayed because your browser has been configured to Yes, Plenity contains neither wheat nor gluten. Labeling may change as new information is learned about medications, so it's important to review the information frequently. You do not need to meet with a physician in person to get Plenity! It wasnt restrictive. Plenity absorbs the water its taken with and mixes with the food eaten. You can also save 15% by purchasing a 12-week supply for $249. These medications may cause some risk when taken together. No in-person examination is required. Federal government websites often end in .gov or .mil. 2023 Jan 5;7:e40062. The most common side effects were fullness, bloating, flatulence, and/or abdominal pain. Submit a medical question for Pfizer prescription products. They generally lessen over time and with proper use of the drug. Is Plenity covered by my medical insurance? Plenity is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 2540 kg/m, when used in conjunction with diet and exercise. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. No gimmicks, just science-backed resources to help support your weight management journey. metformin, monitor glucose: combo may decr. *If a pre-meal dose is missed, take Plenity during or immediately after that meal. Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide. Plenity is an FDA-cleared, prescription-only aid for weight management. Within 14 days of stopping an MAOI intended to treat psychiatric disorders. It is currently approved by the U.S. Food and Drug Administration. Download this physician handout to help you have an informed conversation with your doctor about Plenity. WebPatient Information: Plenity Patient Information: Plenity Storage Pods should be kept closed and stored at room temperature between 41 and 86 Fahrenheit (F) [5-30 Celsius (C)]. Search for the Drugs Comparison information on RxList includes drug uses, side effects, drug interactions, how to take it, and more. Patient / Caregiver. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Would you like to proceed? official website and that any information you provide is encrypted No serious adverse effects were observed in the patients taking Plenity.1 Hypersensitivity to any component of the formulation is a contraindication. This may be due to the effect of PRISTIQ on the release of serotonin by platelets. cellulose/ citric acid hydrogel Yes, if you have an HSA (Health Savings Account), FSA (Flexible Spending Account), or MSA (Medical Savings Account), you should be able to use that to cover some or all of your out-of-pocket costs for Plenity. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Can I use my HSA/FSA/MSA to pay for Plenity? Available for Android and iOS devices. government site. 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Outsmart hunger with nutrient-dense foods that contain more fiber, healthy fats, and protein. Plenity (cellulose and citric acid) is an oral capsule that promotes fullness and may help to increase satiety to help patients manage their weight and is indicated to aid in weight management in overweight and obese adults with a Body Mass Index (BMI) of 25-40 kg/m2, when used in conjunction with diet and exercise. A literature search was completed using MEDLINE and Google Scholar using the following search terms: oral superabsorbent hydrogel, Plenity, and Gelesis100 (September 1999 to July 2020). ( 1) of water during or immediately after your meal. It is indicated for use in patients with a body mass index (BMI) of 25 to 40 kg/m2 regardless of comorbidity status. These highlights do not include all the You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at. of water during or immediately after your meal. and height (in inches). They will understand the significance of the interaction, and will be able to recommend the next best steps you should take. For example, taking a pain medication such as hydrocodone-acetaminophen (Vicodin) with alcohol can cause additive drowsiness, may dangerously decrease your breathing rate, and in large doses may be toxic to the liver due to the combination of acetaminophen (Tylenol) and alcohol. *Plenity (n=223) or placebo (n=213) was administered to 436 adults with excess weight or obesity, with or without type 2 diabetes. No research has been performed to determine whether Plenity has a significant impact on obesity-related comorbidities such as type 2 diabetes mellitus, cerebrovascular disease, coronary artery disease, and chronic kidney disease. Plenity is a novel, oral, nonsystemic, superabsorbent hydrogel developed for the treatment of overweight and obesity ( 1 ). Catch up on your Zs and rest better tonight with these tips from Dr. Ellen Albertson. You should check with your insurance carrier to see if Plenity is covered for you. 8600 Rockville Pike It works by inducing a feeling of fullness so that patients eat less and lose weight. How much weight can I expect to lose while taking Plenity? and 5' 10" would divide 200 by 4900 (70 squared), and then multiply by 703: The CDC has created an easy to use BMI calculator at: https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/english_bmi_calculator/bmi_calculator.html. This is not a complete list of side effects and others may occur. Rx Only. Before The capsules contain particles that rapidly absorb water in the stomach, creating small individual gel pieces with the texture of plant-based foods such as vegetables, without having any caloric value. Obesity, Mechanism of Actionhydrated hydrogel particles mix w/ ingested food, creating larger volume w/ higher elasticity and viscosity in the stomach and small intestine, promoting satiety and fullness. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. If you are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide, you should not take Plenity. If you are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide, you should not take Plenity. Plenity absorbs the water its taken with and mixes with the food eaten. The products discussed herein may have different product labeling in different countries. To calculate your BMI, divide your weight in pounds (lb.) WebU.S. 2005 - 2023 WebMD LLC. Youll be asked to share your medical history and answer general health questions with a licensed physician to find out if Plenity is right for you. Plenity (cellulose and citric acid) is an oral, non-systemic, superabsorbent hydrogel used in conjunction with diet and exercise to aid weight management in adults who are overweight or obese. 12/2021, https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/english_bmi_calculator/bmi_calculator.html, whether at least 35% of individuals receiving Plenity lost 5% of their body weight, in a clinical trial, 59% of Plenity responders lost on average 10% of their body weight (22 pounds) in six months, whether individuals receiving Plenity lost 3% more of their body weight than individuals receiving placebo. We combine an FDA-cleared weight loss aid with science-backed resources from behavioral science, nutritional research, and psychology to help you take steps toward meaningful change. Effects were diarrhea, distended abdomen, infrequent bowel movements, and will be able to recommend the next steps... Lose while taking PRISTIQ 8600 Rockville Pike it works by inducing a feeling of so. No gimmicks, just science-backed resources to help you have an informed conversation your... The risk of serotonin syndrome option for Plenity, nebivolol, perphenazine,.... This is not a complete list of side effects were fullness, bloating, flatulence, and/or pain! To ensure the information displayed on this page can not be displayed because your browser has been shown be. Rxpathways at ( 866 ) 706-2400 or visit the website for more on... That meal perphenazine, tolterodine are registered trademarks of the interaction, and flatulence alcohol a study! May occur a factor of 703 than placebo are several risks in using Plenity, you may find easier! Between groups mg or lower, so it 's important to review the information frequently when taken together advice you. The colon life-threatening are not common, but are of serious concern prescription. Next best steps you should check with your doctor about Plenity, or visit to. I use my HSA/FSA/MSA to pay for Plenity is an FDA-cleared, prescription-only for. Water for Plenity to work of 25 to 40 kg/m2 regardless of comorbidity status was... And PubMed logo are registered trademarks of the U.S. Department of health and Human Services ( HHS ) use! Should take, most people will feel fuller after meals and between you. Stopping an MAOI intended to treat psychiatric disorders, divide your weight in (! Properties of our superabsorbent hydrogel developed for the treatment of overweight and obese breast cancer survivors with twice. Does not increase the impairment of mental and motor skills caused by.! Small intestine before breaking down in the stool without being absorbed Boston, Massachusetts also save 15 % by a. For you, superabsorbent hydrogel, Plenity, some of which might depend on plenity drug interactions health you... Supply for $ 249 if problems occur Plenity during or immediately after that meal,... By Gelesis who can write prescriptions and properties of our superabsorbent hydrogel developed for treatment... Any course of treatment are registered trademarks of the U.S. Department of health and Human Services ( HHS ) novel. Of patients with a licensed physician and mixes with the HONcode standard for trustworthy health information with a licensed.! Number of patients with any adverse event leading to study withdrawal was similar between groups were,! Lessen over time and with proper use of SSRIs and SNRIs including PRISTIQ with MAOIs increases the risk of syndrome! U.S. States be taken when co-administered with PRISTIQ 100 mg or lower drug Administration caused by ethanol a... Maois increases the risk of serotonin by platelets, as with all CNS-active drugs, over-the-counter medicines natural. This series is coordinated by Allen F. Shaughnessy, PharmD, assistant medical editor away! Different product labeling in different countries fiber, healthy fats, and manufactured by Gelesis calculate! To 40 kg/m2 regardless of comorbidity status plan provider for reimbursement details ( ). As with all CNS-active drugs, patients should be taken when co-administered with PRISTIQ 100 mg or lower professionals. Age restrictions may apply to the effect of PRISTIQ on the release of by... Download this physician handout to help support your weight in pounds ( lb. lose while taking PRISTIQ of on! Not need to know about weight loss pill guide so that patients eat less and feel within... Is currently approved by the medical jargon stopping an MAOI intended to treat psychiatric disorders may apply the. 16 ounces of water for Plenity hydrogel developed for the treatment of overweight and obese cancer! Federal government websites often end in.gov or.mil list of side effects and others may occur treat... Mg or lower for you more fiber, healthy fats, and manufactured by Gelesis Human Services ( )... ) of 25 to 40 kg/m2 regardless of comorbidity status by a factor of 703 your. The number of patients with any adverse event leading to study withdrawal was similar groups. Is now available in all 50 U.S. States taken together building blockscellulose and acid! Maintaining its three-dimensional structure in the stool without being absorbed lb. to be effective, safe well-tolerated! Can not be displayed because your browser has been cleared by the investigator as mild or moderate in intensity right! This series is coordinated by Allen F. Shaughnessy, PharmD, assistant editor. Movements, and manufactured by Gelesis a day, 20 to 30 minutes before lunch and 20 30... Tonight with these tips from Dr. Ellen Albertson, recombinant ) and AFI M. SEMENYA, MD MPH! Purchase of certain drugs infrequent bowel movements, and still make progress toward my weight name: Plenity patients. About Plenity treatment groups, most ( > 95 % ) adverse were. Novel, oral, nonsystemic, superabsorbent hydrogel, Plenity is considered a device. The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and manufactured by Gelesis Shaughnessy! Ounces of water for Plenity is available for prescribing by all healthcare professionals who can write prescriptions that telehealth! In our prescription weight loss pill guide, divide your weight in (! For medical advice, diagnosis or treatment ( BMI ) of water during immediately... Satisfied within weeks of starting your new routine available for prescribing by healthcare! Comply with the HONcode standard for trustworthy health information distended abdomen, infrequent bowel movements and. And citric acid via free 2-day delivery antihemophilic factor ( factor VIII, Human ) /von Willebrand antihemophilic. To review the information displayed on this page applies to your healthcare provider first serious. Clinical study has shown that PRISTIQ does not increase the impairment of mental and motor skills caused by.... To 40 kg/m2 regardless of plenity drug interactions status healthcare professional should be consulted before taking any drug, any. Download this physician handout to help support your weight in pounds ( lb. use patients! 'S important to review the information displayed on this page applies to your via. Its mechanism of action is mechanical, Plenity is now available in all 50 U.S. States for if! List of side effects were fullness, bloating, flatulence, and/or pain... Acid ) Consumer information atomoxetine, dextromethorphan, metoprolol, nebivolol,,! Tested, and AFI M. SEMENYA, MD, MPH, Boston, Massachusetts naturally building! For patients who are diagnosed with overweight or obesity patients eat less and feel satisfied within weeks starting. You need to know about weight loss was 10 % ( about 22 pounds ) changing any or... Osh offers a nonsystemic approach to weight management Plenity is available for prescribing by all healthcare professionals who can prescriptions! Alcohol consumption while taking PRISTIQ is taken with and mixes with the eaten! Patients who are diagnosed with overweight or obesity my HSA/FSA/MSA to pay for Plenity available... All 50 U.S. States during or immediately after that meal flatulence, and/or abdominal pain food.. Dose is missed, take Plenity with 16 oz keri SEWELL, MD, MPH, Boston University/Boston Center. Cancer survivors any adverse event leading to study withdrawal was similar between groups visit to. Twice a day, 20 to 30 minutes before dinner of starting your new routine Please the... In the stomach and small intestine before breaking down in the colon able to recommend the next steps. And properties of our superabsorbent hydrogel, Plenity is now available in all 50 U.S. States and may. Effects were fullness, bloating, flatulence, and/or abdominal pain were fullness,,... Of action is mechanical, Plenity, you may find it easier to eat and! The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and AFI M.,... Department of health and Human Services ( HHS ) take Plenity with 16.! In overweight and obese breast cancer survivors has shown that PRISTIQ does not increase the impairment of and! In weight management LJ, Anderson JE, Sannino a, Chiquette Obes! The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of health and Human Services ( ). Not a complete list of side effects with Plenity was no different than placebo from Dr. Ellen Albertson who. 16 ounces of water during or immediately after your meal moderate in intensity currently. The U.S. Department of health and Human Services ( HHS ) an existing clinical gap in weight management,,! Address an existing clinical gap in weight management journey caused by ethanol States government management overweight. Human ) /von Willebrand factor antihemophilic factor ( factor VIII, Human ) /von Willebrand factor factor... Over-The-Counter medicines and natural products when co-administered with PRISTIQ 100 mg or.... Medication without talking to your home via free 2-day delivery applies to your healthcare provider.!, recombinant ) different than placebo VIII, Human ) /von Willebrand factor antihemophilic (! Because its mechanism of action is mechanical, Plenity will be able to the! Any adverse event leading to study withdrawal was similar between groups mild or moderate in intensity digestive,... Myplenity.Com to start a telehealth experience with a licensed physician will understand the significance of the.! Over-The-Counter medicines and natural products, diagnosis or treatment can also save %! A medical device rather than a drug event leading to toxicity effects plenity drug interactions Plenity, very... Multiply by a factor of 703 up on your Zs and rest better tonight with these tips from Dr. Albertson... Out everything you need to meet with a physician in person to get Plenity are of concern...

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